High serum levels of IGF-I and IGFBP3 may increase comorbidity risk for asthmatic patients
نویسندگان
چکیده
منابع مشابه
The effects of tonsillectomy and adenoidectomy on serum IGF-I and IGFBP3 levels in children.
OBJECTIVE Obstructive adenoid and tonsillar hyperplasia may present with retardation of growth. Interruption of growth hormone-insulin-like growth factor I axis resulting from abnormal nocturnal growth hormone secretion is among the postulated causes. Growth hormone (GH) mediates its anabolic effects on tissues through insulin-like growth factor I (IGF-I). Most of the circulating IGF-I is bound...
متن کاملSerum levels of IGF-I and IGF-II in patients with lung cancer during chemotherapy.
UNLABELLED The AIM of this study was to assess the influence of chemotherapy on the serum levels of IGF-I and IGF-II in patients with lung cancer. METHODS The study included 38 patients (33 males and 5 females) at mean age of 59.8, diagnosed histologically with lung cancer. Twenty five patients had non-small cell lung cancer (NSCLC) including 11 patients with squamous cell carcinoma (SCC), 5 ...
متن کاملIntense Walking Exercise Affects Serum IGF-1 and IGFBP3
BACKGROUND Insulin-like growth factor (IGF-1) is associated with chronic diseases such as diabetes, cardiovascular disease, and hypertension, as well as muscle dysfunction. Previous studies of exercise interventions yield controversial results regarding plasma IGF-1, IGFBP3, and IGF-1/IGFBP3 ratio. In this study, we examined whether 100 km walking exercise affects serum levels of IGF-1 and IGFB...
متن کاملIGF-I and IGFBP-3 serum levels in patients hospitalized for complications of liver cirrhosis.
BACKGROUND IGF-I and IGFBP-3 are part of IGF system and, due to their predominantly hepatic synthesis, they seem to correlate with hepatic dysfunction intensity. AIMS To investigate the significance of IGF-I and IGFBP-3 in patients with decompensated liver disease. MATERIAL AND METHODS Cross-sectional study that included cirrhotic patients admitted to hospital due to complications of the di...
متن کاملEvaluation of Serum Levels of Calprotectin in Asthmatic Children
Background Calprotectin is a cytosolic protein that belongs to the S-100 protein group with immunomodulatory and antiproliferative actions. The level of this protein increases in infection, inflammation, and malignancy. The aim of this study was to evaluate the level of...
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ژورنال
عنوان ژورنال: Bratislava Medical Journal
سال: 2017
ISSN: 1336-0345
DOI: 10.4149/bll_2017_130